| Title |
Revision |
Abstract |
Download |
| Spore News - Volume 1, Number 1 |
12/31/2003 |
In this first issue of Spore News, SGM Laboratory Manager Garrett Krushefski discusses reasons why a biological indicator might survive a validated sterilization cycle. |
PDF (0.21MB) |
| Spore News - Volume 1, Number 2 |
02/29/2004 |
SGM President, Dr. John R. Gillis, discusses Bacillus subtilis "5230", a biological indicator for low temperature steam sterilization. |
PDF (0.24MB) |
| Spore News - Volume 1, Number 3 |
05/31/2004 |
R&D Laboratory Manager, Kurt McCauley, discusses the importance of product d-value studies when developing a sterilization process. |
PDF (0.24MB) |
| Spore News - Volume 1, Number 4 |
08/31/2004 |
Spore Lab Supervisor, Kellie Matzinger, writes on 16S rRNA bacterial spore identification and its role in SGM Biotech's quality control program. |
PDF (0.38MB) |
| Spore News - Volume 1, Number 5 |
12/31/2004 |
Consistent Biological Indicators Require Clean Spores - Inter and intra lot reproducibility of Biological Indicators (BIs) is
enhanced by processing techniques to remove debris from spore
suspensions prior to the production of BIs. |
PDF (0.55MB) |
| Spore News - Volume 2, Number 1 |
03/01/2005 |
SGM President, Dr. John R. Gillis, discusses how much variation users should allow when specifying a D-value. |
PDF (0.11MB) |
| Spore News - Volume 2, Number 2 |
Rev. 2, 03/25/2009 |
Laboratory Manager Garrett Krushefski writes on selecting a biological indicator with appropriate resistance performance to monitor a validated sterilization cycle. |
PDF (0.08MB) |
| Spore News - Volume 2, Number 3 |
09/01/2005 |
We receive frequent questions from customers regarding the kill time that appears on the
certificate. The impression it gives is that the kill time is "too long" and the biological
indicators are too resistant. This is a misconception. |
PDF (0.12MB) |
| Spore News - Volume 2, Number 4 |
12/01/2005 |
If you want to know the truth about your sterilization cycle performance, you'll have to ask a spore. A probe only knows one part of the truth and true cycle performance and delivery of lethality is never dependent upon only one critical variable. |
PDF (0.09MB) |
| Spore News - Volume 3, Number 1 |
03/03/2006 |
R&D Lab Manager Kurt McCauley discusses calculating biological indicator d-values and kill times at temperatures not specified on the certificate of analysis. |
PDF (0.14MB) |
| Spore News - Volume 3, Number 2 |
06/30/2006 |
This issue of Spore News focuses on two methods of calculating a Z-value: graphically and mathematically using log-linear regression analysis. Methods to estimate a D-value from a known Z-value are also covered. |
PDF (0.16MB) |
| Spore News - Volume 3, Number 3 |
09/19/2006 |
This issue of Spore News discusses the conditions under which BI D-values are assessed. An evaluation of the lethality delivered in a BIER exposure and how it differs from that in a process vessel will show that requests for specific BI D-values are not necessary when monitoring validated process cycles. |
PDF (0.1MB) |
| Spore News - Volume 3, Number 4 |
11/02/2006 |
Validation engineers face many challenges when validating steam-in-place or sterilization-in-place (SIP) systems. Of great concern is the loss of biological indicators within the expanse of process piping during validation. |
PDF (0.57MB) |
| Spore News - Volume 4, Number 1 |
01/31/2007 |
Spore Lab Supervisor Kellie Matzinger discusses the impact of culture media on biological indicator spore recovery. |
PDF (0.09MB) |
| Spore News - Volume 4, Number 2 |
02/28/2007 |
Production Services Manager Rick Gillis, Ph.D., discusses why biological indicators should be used to monitor routine sterilization. |
PDF (0.16MB) |
| Spore News - Volume 4, Number 3 |
05/01/2007 |
There are two aspects that together determine the overall resistance capabilities of a biological indicator: population and D-value. This edition of Spore News will evaluate these two aspects as well as discuss how specific one really needs to be when ordering a new lot of indicators. |
PDF (0.09MB) |
| Spore News - Volume 4, Number 4 |
07/01/2007 |
Production Services Manager Rick Gillis, Ph.D. discusses the history and significance of reduced incubation time (RIT). |
PDF (0.46MB) |
| Spore News - Volume 4, Number 5 |
09/26/2007 |
John R. Gillis, Ph.D. explains why live spores from biological indicators are not a contamination threat. |
PDF (0.08MB) |
| Spore News - Volume 4, Number 6 |
11/29/2007 |
Whether you're cooking spores or baking brownies, you'll probably want to don your chef's hat and apron for this latest edition of Spore News: Verification Testing With Different Media is a Waste of Time. |
PDF (0.25MB) |
| Spore News - Volume 5, Number 1 |
01/30/2008 |
A major misunderstanding in the industry is that spores have an intrinsic D-value. This is not true. It is the resistance of the system that is measured, not simply the spores. |
PDF (2.23MB) |
| Spore News - Volume 5, Number 2 |
03/30/2008 |
When sterilizing by steam, it is imperative to first remove ambient air not only from the chamber but also from the devices being sterilized. Failure to do so can result in undetected sterilization failure. |
PDF (2.15MB) |
| Spore News - Volume 5, Number 3 |
05/29/2008 |
The spores used in biological indicators should be clean and free of vegetative cells as well as all other cellular debris. The purpose of the heat shock in a population assay of a BI is primarily the heat activation of spores. |
PDF (0.25MB) |
| Spore News - Volume 5, Number 4 |
08/06/2008 |
Glassine packaged vs. naked carrier D-values. |
PDF (0.24MB) |
| Spore News - Volume 5, Number 5 |
Rev. 1, 09/30/2008 |
This issue of Spore News focuses on how to use the Z-value to determine the total lethality delivered in a sterilization process. |
PDF (0.18MB) |
| Spore News - Volume 5, Number 6 |
11/26/2008 |
Using Lethality Mapper software to find the "worst case" location in your sterilizer load. |
PDF (1.08MB) |
| Spore News - Volume 6, Number 1 |
01/31/2009 |
Time to take the guesswork out of your sterilization process -- apply accurate biological and physical information. |
PDF (0.31MB) |
| Spore News - Volume 6, Number 2 |
03/31/2009 |
The biological indicator spore
population has minimal impact on
resistance performance. |
PDF (0.2MB) |
| Spore News - Volume 6, Number 3 |
06/01/2009 |
Introducing SterilFlex, a liquid submersible, glass-free biological indicator for the food industry. |
PDF (0.13MB) |
| Spore News - Volume 6, Number 4 |
07/31/2009 |
How long should biological indicators be incubated? |
PDF (0.11MB) |
| Spore News - Volume 6, Number 5 |
09/29/2009 |
Disinfection versus sterilization. |
PDF (0.5MB) |
| Spore News - Volume 6, Number 6 |
11/01/2009 |
Defining boundaries: the beauty of a self-contained biological indicator (SCBI) |
PDF (0.12MB) |
| Spore News - Volume 7, Number 2 |
04/01/2010 |
In the August 2007 issue of Pharmaceutical Technology1 magazine, we published an article on the performance of a new design of steam resistometer produced by Fedegari Autoclavi SpA (Pavia, Italy). Since the publication we have collected additional data on other organisms in the Fedegari resistometer and will report these results here. |
PDF (0.29MB) |
| Spore News - Volume 7, Number 3 |
Rev. 1, 05/31/2010 |
SGM Biotech is pleased to announce the introduction of its newest product line, the Process Challenge Device (PCD) for use externally on pallets processed in Ethylene Oxide sterilization. |
PDF (0.2MB) |
| Spore News - Volume 7, Number 4 |
08/01/2010 |
Read out times of Smart-Read EZTest exposed at elevated temperatures. |
PDF (0.45MB) |
